Recent publications and landmark papers from the McDevitt group are listed below. Reprints can be provided upon request.

For a full list of publications and book chapters:

Refereed Journal Articles

Reviews and Book Chapters

Citation rates can be found at Google Scholar or Researcher ID

Article level metrics, as recommended in the San Francisco Declaration on Research Assessment (DORA), for selected publications below are reported by Altmetric

Recent Publication Highlights

Maunders, E.A., Ngu, D.H.Y., Ganio, K., Hossain, S.I., Lim, B.Y.J., Leeming, M.G., Luo, Z., Tan, A., Deplazes, E., Kobe, B., McDevitt, C.A. (2022) The Impact of Chromate on Pseudomonas aeruginosa Molybdenum Homeostasis. Frontiers in Microbiology 13:903146. doi: 10.3389/fmicb.2022.903146

Brazel, E.B., Tan, A., Neville, S.L., Iverson, A.R., Udagedara, S.R., Cunningham, B.A., Sikanyika, M., De Oliveira, D.M.P., Keller, B., Bohlmann, L., El-Deeb, I.M., Ganio, K., Eijkelkamp, B.A., McEwan, A.G., von Iztstein, M., Maher, M.J., Walker, M.J., Rosch, J.W., McDevitt, C.A. (2022) Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks resistance to ampicillin in a pneumonia infection model. Cell Reports. 38:110202. doi: 10.1016/j.celrep.2021.110202


Leiter, O., Zhuo, Z., Rust, R., Wasielewska, J.M., Grönnert, L., Kowal, S., Overall, R.W., Adusumilli, V.S., Blackmore, D.G., Southon, A., Ganio, K., McDevitt, C.A., Rund, N., Brici, D., Aththanayake Mudiyan, I., Sykes, A.M. Rünker, A.E., Zocher, S., Ayton, S., Bush, A.I., Bartlett, P.F., Hou, S-T., Kempermann, G., Walker, T.L. (2022) Selenium mediates the exercise-induced increase in neurogenesis and reverses the learning deficits induced by hippocampal injury and ageing. Cell Metabolism. doi: 10.1016/j.cmet.2022.01.005


De Oliveira, D.M.P., Forde, B.M., Phan, M-D., Steiner, B., Zhang, B., Zuegg, J., El-Deeb, I.M., Li, G., Keller, N., Brouwer, S., Harbison-Price, N., Cork, A.J., Bauer, M.J., Beatson, S.A., Roberts, J.A., Paterson, D.L., McEwan, A.G., Blaskovich, M.A.T., Schembri, M.A., McDevitt, C.A., von Itzstein, M., Walker, M.J. (2022) Rescuing tetracycline class antibiotics for the treatment of multidrug resistant Acinetobacter baumannii pulmonary infection. mBio. 13:e03517-21 doi: 10.1128/mbio.03517-21


Ouyang, A., Gasner, K.M., Neville, S.L., McDevitt, C.A., Frawley, E.R. (2022) MntP and YiiP contribute to manganese efflux in Salmonella enterica serovar Typhimurium under conditions of manganese overload and nitrosative stress. Microbiology Spectrum. 10:e01316-21. doi: 10.1128/spectrum.01316-21

Maunders, E.A., Hayes, A.J., Ganio, K., Neville, S.L., Davies, M.R., Strugnell, R., McDevitt, C.A., Tan, A. (2022) The role of ZntA in Klebsiella pneumoniae zinc homeostasis. Microbiology Spectrum. 10:e01773-21. doi:10.1128/spectrum.01773-21

Neville, S.L., Sjöhamn, J., Watts, J.A., MacDermott-Opeskin, H., Fairweather, S.J., Ganio, K., Carey Hulyer, A., McGrath, A.P., Hayes, A.J., Malcolm, T.R., Davies, M.R., Nomura, N., Iwata, S., O'Mara, M.L., Maher, M.J., McDevitt, C.A. (2021) The structural basis of bacterial manganese import. Science Advances. 7(32):eabg3980. doi: 10.1126/sciadv.abg3980


Župan, M.L., Luo, Z., Ganio, K., Pederick, V.G., Neville, S.L., Deplazes, E., Kobe, B., McDevitt, C.A. (2021) Conformation of the solute-binding protein AdcAII influences zinc uptake in Streptococcus pneumoniae. Frontiers in Cellular and Infection Microbiology. 11:729981. doi: 10.3389/fcimb.2021.729981


Luo, Z., Morey, J.R., Deplazes, E., Motygullina, A., Tan, A., Ganio, K., Neville, S.L., Eleftheriadis, N., Isselstein, M., Pederick, V.G., Paton, J.C., Cordes, T., Harmer, J.R., Kobe, B., McDevitt, C.A. (2021) A trap-door mechanism for zinc acquisition by Streptococcus pneumoniae AdcA. mBio. 12:e01958-20. doi: 10.1128/mBio.01958-20


Neville, S.L., Eijkelkamp, B.A., Lothian, A., Paton, J.C., Roberts, B.R., Rosch, J.W., McDevitt, C.A. (2020) Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae. Communications Biology. 3:694. doi: 10.1038/s42003-020-01417-y


Cooper, V., Honsa, E., Rowe, H., Deitrick, C., Iverson, A., McDevitt, C.A., Kietzman, C., and Rosch, J.W. (2020) Experimental evolution in vivo to identify selective pressures during pneumococcal colonization. mSystems. 5:e00352-20. doi: 10.1128/mSystems.00352-20


De Oliveira, D.M.P., Bohlmann, L., Conroy, T., Jen, F.E., Everest-Dass, A., Hansford, K.A., Bolisetti, R., El-Deeb, I.M., Forde, B.M., Phan, M.D., Lacey, J.A., Tan, A., Rivera-Hernandez, T., Brouwer, S., Keller, N., Kidd, T.J., Cork, A.J., Bauer, M.J., Cook, G.M., Davies, M.R., Beatson, S.A., Paterson, D.L., McEwan, A.G., Li, J., Schembri, M,A., Blaskovich, M.A.T., Jennings, M.P., McDevitt, C.A., von Itzstein, M., Walker, M.J. (2020) Repurposing a neurodegenerative disease drug to treat Gram-negative antibiotic-resistant bacterial sepsis. Science Translation Medicine. 12:eabb3791. doi: 10.1126/scitranslmed.abb3791


Eijkelkamp, B.A., Morey, J.R., Neville, S.L., Tan, A., Pederick, V.G., Cole, N., Singh, P.P., Ong, C-L.Y., Gonzalez de Vega, R., Clases, D., Cunningham, B.A., Hughes, C.E., Comerford, I., Brazel, E.B., Whittall, J.J., Plumptre, C.D., McColl, S.R., Paton, J.C., McEwan, A.G., Doble P.A., and McDevitt, C.A. (2019) Dietary zinc and the control of Streptococcus pneumoniae infection. PLoS Pathogens. 15:e1007957. doi: 10.1371/journal.ppat.1007957


Monk, I.R., Shaikh, N., Begg, S.L., Gajdiss, M., Sharkey, L.K.R., Lee, J.H.Y., Pidot, S.J., Seemann, T., Kuiper, M., Winnen, B., Hvorup, R., Collins, B.M., Bierbaum, G., Udagedara, S.R., Morey, J.R., Pulyani, N., Howden, B.P., Maher, M.J., McDevitt, C.A., King, G.F., and Stinear, T.P. (2019) Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Nature Communications. 10:3067. doi: 10.1038/s41467-019-10932-4


de Boer M., Gouridis G., Vietrov R., Begg S.L., Schuurman-Wolters G.K., Husada F., Eleftheriadis N., Poolman B., McDevitt C.A., Cordes T. (2019) Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers. eLife. 8:e44652. doi: 10.7554/eLife.44652


Jiang JH, Hassan KA, Begg SL, Rupasinghe TWT, Naidu V, Pederick VG, Khorvash M, Whittall JJ, Paton JC, Paulsen IT, McDevitt CA, Peleg AY, Eijkelkamp BA. (2019) Identification of novel Acinetobacter baumannii host fatty acid stress adaptation strategies. mBio. 10:e02056-18. doi: 10.1128/mBio.02056-18


Bohlmann, L., De Oliveira, D.M.P., El-Deeb, I.M., Brazel, E.B., Harbison-Price, N., Ong, C-Y., Rivera-Hernandez, T., Ferguson, S.A., Cork, A.J., Phan, M.D., Soderholm, A.T., Davies, M.R., Nimmo, G.R., Dougan, G., Schembri, M.A., Cook, G.M., McEwan, A.G., von Itzstein, M., McDevitt, C.A., Walker, M.J. (2018) Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio. 9:e02391-18. doi: 10.1128/mBio.02391-18.


Kidsley, A.K., Abraham, S., Bell, J.M., O'Dea, M., Laird, T.J., Jordan, D., Mitchell, P., McDevitt, C.A., Trott, D.J. (2018) Antimicrobial susceptibility of Escherichia coli and Salmonella spp. isolates from healthy pigs in Australia: Results of a pilot national survey. Frontiers in Microbiolology. 9:1207. doi: 10.3389/fmicb.2018.01207

Eijkelkamp, B.A., Begg, S.L., Pederick, V.G., Trapetti, C., Gregory, M.K., Whittall, J.J., Paton, J.C. and McDevitt, C.A. (2018) Arachidonic acid stress impacts pneumococcal fatty acid homeostasis. Frontiers in Microbiolology. 9:813. doi: 10.3389/fmicb.2018.00813

Grim, K., San Francisco, B. Radin, J., Brazel, E.B., Kelliher, J., Párraga Solórzano, P. Kim, P., McDevitt, C.A. and Kehl-Fie, T. (2017) The metallophore staphylopine enables Staphylococcus aureus to compete with the host for zinc and overcome nutritional immunity. mBio. e01281-17. doi: 10.1128/mBio.01281-17

Trappetti, C., McAllister, L.J., Chen, A., Wang, H., Paton, A.W., Oggioni, M.R., McDevitt, C.A., and Paton, J.C. (2017) Autoinducer 2 signaling via the phosphotransferase FruA drives galactose utilization by Streptococcus pneumoniae, resulting in hypervirulence. mBio. 8: e02269-16. doi: 10.1128/mBio.02269-16

Bajaj, M., Mamidyala, S.K., Zuegg, J., Begg, S.L., Ween, M.P., Luo, Z., Huang, J.X., McEwan, A.G., Kobe, B., Paton, J.C., McDevitt, C.A., and Cooper M.A. (2015) Discovery of novel Pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach. ACS Chemical Biology. 10:1511-20. doi: 10.1021/cb501032x

Pederick, V.G., Eijkelkamp, B.A., Begg, S.L., Ween, M.P., McAllister, L.J., Paton, J.C., and McDevitt, C.A. (2015) ZnuA and zinc homeostasis in Pseudomonas aeruginosa. Scientific Reports. 5:13139. doi: 10.1038/srep13139

Begg, S.L., Eijkelkamp, B.A., Luo, Z., Couñago, R.M., Morey, J.R., Maher, M.J., Ong C.Y., McEwan, A.G., Kobe, B., O'Mara M.L., Paton, J.C., and McDevitt, C.A. (2015) Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nature Communications. 6:6418. doi: 10.1038/ncomms7418


Plumptre, C.D.*, Eijkelkamp, B.A.*, Morey, J.R., Behr, F., Couñago, R.M., Ogunniyi, A.D., Kobe B., O'Mara, M.L., Paton, J.C., and McDevitt, C.A. (2014) AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology. 91:834-51. doi: 10.1111/mmi.12504. [*equal first author]

Couñago, R.M.*, Ween, M.P.*, Begg S.L., Bajaj, M., Zuegg, J., O'Mara, M.L., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., and McDevitt, C.A. (2014) Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology. 10:35-41. doi: 10.1038/nchembio.1382 [*equal first author]


McDevitt, C.A., Ogunniyi, A.D., Valkov, E., Lawrence, M.C., Kobe, B., McEwan, A.G., and Paton, J.C. (2011) A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens. 7:e1002357 doi: 10.1371/journal.ppat.1002357

McDevitt, C.A., Collins R.F., Conway M., Modok S., Storm J., Kerr I.D., Ford R.C. and Callaghan R. (2006) Purification and 3-D structural analysis of oligomeric human multidrug transporter ABCG2. Structure 14:1623-32. doi: 10.1016/j.str.2006.08.014

Gohlke, U., Pullen, L., McDevitt, C.A., Porcelli, I., Palmer, T., Sabil, H.R. and Berks, B.C. (2005) The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter. Proceedings of the National Academy of Sciences of the United States of America. 102:10482-6. doi: 10.1073/pnas.0503558102