Recent publications and landmark papers from the McDevitt group are listed below. Reprints can be provided upon request.

For a full list of publications and book chapters:

Refereed Journal Articles

Reviews and Book Chapters

Citation rates can be found at Google Scholar or Researcher ID

Article level metrics, as recommended in the San Francisco Declaration on Research Assessment (DORA), for selected publications below are reported by Altmetric

Recent Publications

Eijkelkamp, B.A., Morey, J.R., Neville, S.L., Tan, A., Pederick, V.G., Cole, N., Singh, P.P., Ong, C-L.Y., Gonzalez de Vega, R., Clases, D., Cunningham, B.A., Hughes, C.E., Comerford, I., Brazel, E.B., Whittall, J.J., Plumptre, C.D., McColl, S.R., Paton, J.C., McEwan, A.G., Doble P.A., and McDevitt, C.A. (2019) Dietary zinc and the control of Streptococcus pneumoniae infection. PLoS Pathogens doi: 10.1371/journal.ppat.1007957


Monk, I.R., Shaikh, N., Begg, S.L., Gajdiss, M., Sharkey, L.K.R., Lee, J.H.Y., Pidot, S.J., Seemann, T., Kuiper, M., Winnen, B., Hvorup, R., Collins, B.M., Bierbaum, G., Udagedara, S.R., Morey, J.R., Pulyani, N., Howden, B.P., Maher, M.J., McDevitt, C.A., King, G.F., and Stinear, T.P. (2019) Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Nature Communications doi: 10.1038/s41467-019-10932-4

de Boer M., Gouridis G., Vietrov R., Begg S.L., Schuurman-Wolters G.K., Husada F., Eleftheriadis N., Poolman B., McDevitt C.A., Cordes T. (2019) Conformational and dynamic plasticity in substrate-binding proteins underlies selective transport in ABC importers. eLife doi: 10.7554/eLife.44652.

Moulin P., Rong V., Ribeiro E Silva A., Pederick V.G., Camiade E., Mereghetti L., McDevitt C.A., Hiron A. (2019) Defining the Role of the Streptococcus agalactiae Sht-Family Proteins in Zinc Acquisition and Complement Evasion. J Bacteriol. doi: 10.1128/JB.00757-18

Jiang JH, Hassan KA, Begg SL, Rupasinghe TWT, Naidu V, Pederick VG, Khorvash M, Whittall JJ, Paton JC, Paulsen IT, McDevitt CA, Peleg AY, Eijkelkamp BA. (2019) Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies. mBio doi: 10.1128/mBio.02056-18

Alquethamy S.F., Khorvash M., Pederick V.G., Whittall J.J., Paton J.C., Paulsen I.T., Hassan K.A., McDevitt C.A., Eijkelkamp B.A. (2019)  The Role of the CopA Copper Efflux System in Acinetobacter baumannii Virulence. Int J Mol Sci. doi: 10.3390/ijms20030575

Sikanyika, M., Aragão, D., McDevitt, C.A., Maher, M.J. (2019) The structure and activity of the glutathione reductase from Streptococcus pneumoniae. Acta Crystallogr F Struct Biol Commun. 75:54-61. doi: 10.1107/S2053230X18016527

Radin, J.N., Zhu, J., Brazel, E.B., McDevitt, C.A., Kehl-Fie, T.E. (2019) Synergy between nutritional immunity and independent host defenses contributes to the importance of the MntABC manganese transporter during Staphylococcus aureus Infection. Infect Immun.  doi: 10.1128/IAI.00642-18.

Bohlmann, L., De Oliveira, D.M.P., El-Deeb, I.M., Brazel, E.B., Harbison-Price, N., Ong, C-Y., Rivera-Hernandez, T., Ferguson, S.A., Cork, A.J., Phan, M.D., Soderholm, A.T., Davies, M.R., Nimmo, G.R., Dougan, G., Schembri, M.A., Cook, G.M., McEwan, A.G., von Itzstein, M., McDevitt, C.A., Walker, M.J. (2018) Chemical synergy between ionophore PBT2 and zinc reverses antibiotic resistance. mBio. doi: 10.1128/mBio.02391-18.

Young, R.J., Begg, S.L., Coghlan, C.J., McDevitt, C.A., Sumby, C.J. (2018) Exploring the use of structure and polymer incorporation to tune silver ion release and antibacterial activity of silver coordination polymers. European Journal of Inorganic Chemistry. 30:3512-18

Karami, A., Zhang, H., Pederick, V.G., McDevitt, C.A., Kabir, M.S., Xu, S., Munroe, P., Zhou, Z., Xie, A. (2018) Cr–Ag coatings: synthesis, microstructure and antimicrobial properties. Surface Engineering doi: 10.1080/02670844.2018.1537082

Zhang, X., Heng, S., Pei, J., Morey, J.R., McDevitt, C.A., Abell, A.D. (2018) A liposomal platform for sensing of extracellular analytes near cells. Biosensors (Basel). doi: 10.3390/bios8040117

Kidsley, A.K., Abraham, S., Bell, J.M., O'Dea, M., Laird, T.J., Jordan, D., Mitchell, P., McDevitt, C.A., Trott, D.J. Antimicrobial susceptibility of Escherichia coli and Salmonella spp. isolates from healthy pigs in Australia: Results of a pilot national survey. Front Microbiol. 9:1207. doi: 10.3389/fmicb.2018.01207

Luo, Z., Pederick, V.G., Paton, J.C., McDevitt, C.A., Kobe, B. (2018) Structural characterisation of the HT3 motif of the polyhistidine triad protein D from Streptococcus pneumoniae. FEBS Lett. 592:2341-2350. doi: 10.1002/1873-3468.13122.

Eijkelkamp, B.A., Begg, S.L., Pederick, V.G., Trapetti, C., Gregory, M.K., Whittall, J.J., Paton, J.C. and McDevitt, C.A. (2018) Arachidonic acid stress impacts pneumococcal fatty acid homeostasis. Frontiers in Microbiology. 9:813 [pdf]

Satiaputra, J., Eijkelkamp, B.A., McDevitt, C.A., Shearwin, K.E., Booker, G.W., Polyak, S.W. (2018) Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin. Applied Microbiology and Biotechnology.  102:3793-3803 [pdf]

Ryan, T.M.,Trewhella, J., Murphy, J.M., Keown, J.R., Casey, L., Pearce, F.G., Goldstone, D.C., Chen, K., Luo, Z., Kobe, B., McDevitt C.A., Watkin, S.A., Hawley, A.M., Mudie, S.T., Samardzic Boban V. and Kirby, N. (2018) An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis. Journal of Applied Crystallography. 50:1-15

Grim, K., San Francisco, B. Radin, J., Brazel, E.B., Kelliher, J., Párraga Solórzano, P. Kim, P., McDevitt, C.A. and Kehl-Fie, T. (2017) The metallophore staphylopine enables Staphylococcus aureus to compete with the host for zinc and overcome nutritional immunity. mBio. 8:e01281-17 [pdf]

Eyre, N.S., Johnson, S.M., Eltahla, A.A., Aloi, M., Aloia, A.L., McDevitt, C.A., Bull, R.A. and Beard, M.R. (2017) Genome-wide mutagenesis of dengue virus reveals plasticity of the NS1 protein and enables generation of infectious tagged reporter viruses. Journal of Virology. 91:e01455-1 [pdf]

Martin, J.M., Edmonds, K.A., Bruce, K.E., Campanello, G.C., Eijkelkamp, B.A., Brazel, E.B., McDevitt, C.A., Winkler, M.E., and Giedroc, D.P. (2017) The zinc efflux activator SczA protects Streptococcus pneumoniae 1 serotype 2 D39 from intracellular zinc toxicity Molecular Microbiology. 104:636-51 [pdf]

Hassan, K.A., Pederick, V.G., Elbourne, L.D.H., Paulsen, I.T., Paton, J.C., McDevitt, C.A.# and Eijkelkamp B.A.# (2017) Zinc stress induces copper depletion in Acinetobacter baumannii. BMC Microbiology. 17:59 (#co-corresponding authors) [pdf]

Trappetti, C., McAllister, L.J., Chen, A., Wang, H., Paton, A.W., Oggioni, M.R., McDevitt, C.A., and Paton, J.C. (2017) Autoinducer 2 signaling via the phosphotransferase FruA drives galactose utilization by Streptococcus pneumoniae, resulting in hypervirulence. mBio. 8: e02269-16 [pdf]

Heng, S., McDevitt, C.A., Kostecki, R., Morey, J.R., Eijkelkamp, B.A., Monro, T., Abell, A.D. (2016) Microstructured optical fiber-based biosensors: Reversible and nanoliter-scale measurement of zinc ions. ACS Applied Materials and Interfaces. 8:12727-32

Luo, Z., Morey, J.R., McDevitt, C.A., Kobe B. Heterogeneous nucleation is required for crystallization of the ZnuA domain of pneumococcal AdcA. (2015) Acta Crystallogr. F Struct. Biol. Commun. 71:1459-1464

Eijkelkamp, B.A., Pederick, V.G., Plumptre, C.D., Harvey, R.M., Hughes, C.E., Paton, J.C., McDevitt, C.A. The first histidine triad motif of PhtD is critical for zinc homeostasis in Streptococcus pneumoniae. (2015) Infection and Immunity. 84:407-415 [pdf]

Deplazes, E.*, Begg, S.L.*, van Wonderen, J.H., Cambpell, R., Kobe, B. Paton, J.C., MacMillan F., McDevitt, C.A.# and O'Mara M.L.# (2015) Characterising the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy. Biophysical Chemistry. 207:51-60 [pdf] [*equal first author; #co-corresponding authors]

Pederick, V.G., Eijkelkamp, B.A., Begg, S.L., Ween, M.P., McAllister, L.J., Paton, J.C., and McDevitt, C.A. (2015) ZnuA and zinc homeostasis in Pseudomonas aeruginosa. Scientific Reports. 5:13139 [pdf]

Begg, S.L., Eijkelkamp, B.A., Luo, Z., Couñago, R.M., Morey, J.R., Maher, M.J., Ong C.Y., McEwan, A.G., Kobe, B., O'Mara M.L., Paton, J.C., and McDevitt, C.A. (2015) Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nature Communications. 6:6418 [pdf]

Bajaj, M., Mamidyala, S.K., Zuegg, J., Begg, S.L., Ween, M.P., Luo, Z., Huang, J.X., McEwan, A.G., Kobe, B., Paton, J.C., McDevitt, C.A., and Cooper M.A. (2015) Discovery of novel Pneumococcal surface antigen A (PsaA) inhibitors using a fragment-based drug design approach. ACS Chemical Biology 10:1511-20 [pdf]

Pederick, V.G., Eijkelkamp, B.A., Ween, M.P., Begg, S.L., Paton, J.C. and McDevitt, C.A. (2014) The acquisition and role of molybdate in Pseudomonas aeruginosa. Applied and Environmental Microbiology. 80:6843-6852 [pdf]

Plumptre, C.D., Hughes, C.E., Harvey, R.M., Eijkelkamp, B.A., McDevitt, C.A. and Paton, J.C. (2014) Overlapping functionality of the Pht proteins in zinc homeostasis of Streptococcus pneumoniae. Infection and Immunity. 82:4315-4324 [pdf]

van Wonderen J.H., McMahon R.M., O'Mara M.L., McDevitt C.A., Thomson A.J., Kerr I.D., MacMillan F., and Callaghan R. (2014) The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis. FEBS Journal. 281:2190-201 [pdf]

Eijkelkamp, B.A., Morey, J.R., Ween, M.P., Ong, C.Y., McEwan, A.G., Paton, J.C., and McDevitt, C.A. (2014) Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in Streptococcus pneumoniaePLoS ONE. 9:e89427 [pdf]

Plumptre, C.D.*, Eijkelkamp, B.A.*, Morey, J.R., Behr, F., Couñago, R.M., Ogunniyi, A.D., Kobe B., O'Mara, M.L., Paton, J.C., and McDevitt, C.A. (2014) AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology. 91:834-51 [pdf] [*equal first author]

Couñago, R.M.*, Ween, M.P.*, Begg S.L., Bajaj, M., Zuegg, J., O'Mara, M.L., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., and McDevitt, C.A. (2014) Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology. 10:35-41. [pdf] [*equal first author]
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McDevitt, C.A., Ogunniyi, A.D., Valkov, E., Lawrence, M.C., Kobe, B., McEwan, A.G., and Paton, J.C. (2011) A molecular mechanism for bacterial susceptibility to zinc. PLoS Pathogens 7:e1002357 [pdf]

Research highlight in Nature Reviews Microbiology - David, R. (2012)

Ogunniyi, A.D., Mahdi, L.K., Jennings, M.P., McEwan, A.G., McDevitt C.A., Van der Hoek, M.B., Bagley, C.J., Hoffman, P., Gould, K.A., and Paton, J.C. (2010) Central role of manganese in regulation of stress responses, physiology and metabolism in Streptococcus pneumoniae. Journal of Bacteriology 192:4489-97. [pdf]

McDevitt, C.A., Collins R.F., Conway M., Modok S., Storm J., Kerr I.D., Ford R.C. and Callaghan R., (2006) Purification and 3-D structural analysis of oligomeric human multidrug transporter ABCG2. Structure 14:1623-32 [pdf]

Gohlke, U., Pullen, L., McDevitt, C.A., Porcelli, I., Palmer, T., Sabil, H.R. and Berks, B.C. (2005) The TatA component of the twin-arginine protein transport system forms channel complexes of variable diameter. Proc. Natl. Acad. Sci. 102:10482-10486 [pdf]